Factors Associated With Hepatitis B Incidence In Pregnant Women
DOI:
https://doi.org/10.32807/jkp.v20i1.1951Keywords:
Hepatitis B, Factor Assosiated, Pregnant WomenAbstract
Hepatitis B remains a significant public health concern and can be transmitted vertically from mother to child. Screening among pregnant women is implemented through the national triple elimination program to prevent mother-to-child transmission. Identifying associated risk factors is essential to strengthen preventive strategies. This study aimed to determine factors associated with hepatitis B infection among pregnant women.A cross-sectional study was conducted at a community health center in Mataram City. The population consisted of 56 pregnant women diagnosed with hepatitis B in 2024. Using a 1:1 ratio of hepatitis B-positive and hepatitis B-negative pregnant women, with an additional 10% to anticipate dropouts, the final sample comprised 122 respondents selected through purposive sampling based on inclusion and exclusion criteria.Bivariate analysis using the Chi-square test showed significant associations between hepatitis B infection and maternal knowledge (p = 0.001) as well as age (p = 0.021). Attitude, family support, health worker support, education, employment status, and parity were not significantly associated (p > 0.05). Logistic regression analysis (? = 5%) confirmed that knowledge (p = 0.000) and age (p = 0.027) were significantly related to hepatitis B infection. At ? = 10%, education also showed a significant association (p = 0.070).Multivariate logistic regression revealed that knowledge (OR = 3.892; p = 0.000), education (OR = 2.682; p = 0.011), and age (OR = 0.298; p = 0.027) were significant predictors, collectively explaining 30.2% of hepatitis B incidence. In conclusion, maternal knowledge, age, and education are significantly associated with hepatitis B infection among pregnant women.
References
Ahad, M., Wallace, J., Xiao, Y., van Gemert, C., Bennett, G., Darby, J., Desmond, P., Hall, S., Holmes, J., Papaluca, T., Glasgow, S., Thompson, A., Hellard, M., Doyle, J., & Howell, J. (2022). Hepatitis B and pregnancy: understanding the experiences of care among pregnant women and recent mothers in metropolitan Melbourne. BMC Public Health,22(1), 1–9. https://doi.org/10.1186/s12889-022-13112-0
Al-Essa, M., Alyahya, A., Al Mulhim, A., Alyousof, A., Al-mulhim, M., & Essa, A. (2020). Perception of and Attitude towards Hepatitis B Infection among Saudi Pregnant Females Attending Antenatal Care Unit in Al-Ahsa City, Kingdom of Saudi Arabia. Cureus, 12(1), 1–12. https://doi.org/10.7759/cureus.6673
Alaridah, N., Abu-Mutaw’, S., Abu-Assaf, G., Al Dwikat, L., F. Jarrar, R., Abuhani, H. O., Al-Hawadi, B., Alhawadi, S., Al Shdifat, M., & Joudeh, R. M. (2024). Sociodemographic Determinants of Knowledge, Attitudes, and Practices Toward Hepatitis B Infection Among Pregnant Women: A Cross-National Study in Jordan. Cureus, 16(4). https://doi.org/10.7759/cureus.58053
Bardoe, D., Hayford, D., Bio, R. B., & Yar, D. D. (2025). Prevalence and Correlates of Hepatitis B in Pregnancy: Evidence From a Cross-Sectional Study in Bono East Region, Ghana. Health Science Reports, 8(9), 1–14. https://doi.org/10.1002/hsr2.71263
Belay, A., Assefa, A., Zeleke, F. T., Animaw, M., Argaw, M., Endeshaw, F., Alemu, S. B., Sahile, A., & Abera, M. (2025). Knowledge, attitudes, and factors associated with vertical transmission of hepatitis B among pregnant women in Gurage Zone, Ethiopia. Scientific Reports, 15(1), 1–11. https://doi.org/10.1038/s41598-025-94010-4
BKPK Kemenkes RI. (2023). Survei Kesehatan Indonesia. In Jakarta. https://www.badankebijakan.kemkes.go.id/ski-2023-dalam-angka/
Dikes Kota Mataram. (2024). PWS KIA.
Diniarti, F., Rohani, T., & Prasentya, W. (2022). Determinant Factors of Hepatitis B Incidence On Pregnant Women. Jurnal Riset Kesehatan Poltekkes Depkes Bandung, 14(1), 197–205. https://mail.juriskes.com/index.php/jrk/article/view/1971
Eberwein, A. E., Cummings, P. R., Cummings, D., Andre, J., & Jacobsen, K. H. (2025). Hepatitis B (HBsAg) prevalence among obstetric patients in Caluquembe, Angola, 2023–2024. Plos One, 20(7 July), 2023–2024. https://doi.org/10.1371/journal.pone.0327426
Foffou, F. L. M., Ketchaji, A., Djoko, G. R. P., Njajou, O. T., & Nkenfou, C. N. (2025). Factors associated with low screening for viral hepatitis B in pregnant women in the Djoungolo Health District in Yaounde, Cameroon. Discover Public Health, 22(1). https://doi.org/10.1186/s12982-025-00954-3
Inayah, D. (2022). Determinan Pemeriksaan Triple Eliminasi Ibu Hamil di Desa Sukaresmi Kecamatan Megamendung Tahun 2021. Indonesia Journal of Midwifery Sciences, 1(4), 125–135. https://doi.org/10.53801/ijms.v1i4.49
Liu, H., Hong, J., Yan, Z., Li, M., Zhai, X., Pan, B., & Ling, C. (2025). Hepatitis B Virus Knowledge and HBV-Related Surveillance Status Among HBsAg-Positive Patients in Qidong City: A Rural-Based Cross-Sectional Survey. Healthcare (Switzerland), 13(1), 1–12. https://doi.org/10.3390/healthcare13010017
Liu, X., Chen, C., Jiang, D., Yan, D., Zhou, Y., Ding, C., Lan, L., Huang, C., Zhang, X., Li, L., & Yang, S. (2022). Psychological stress; Knowledge, attitude and practice and acceptance of antiviral therapy in pregnant women with hepatitis B in Zhejiang, China: A case comparison study. BMJ Open, 12(3). https://doi.org/10.1136/bmjopen-2021-055642
Lobstein, S., Faber, R., & Tillmann, H. L. (2010). Prevalence of hepatitis B among pregnant women and its impact on pregnancy and newborn complications at a tertiary Hospital in the eastern part of Germany. Digestion, 83(1–2), 76–82. https://doi.org/10.1159/000320455
Ngu, S. F., Cheung, A. N. Y., Jong, K. K., Law, J. Y. P., Lee, A. Y., Lee, J. H. S., Li, W. H., Ma, V., Wong, G. C. Y., Wong, R. W. C., & Chan, K. K. L. (2024). 2024 Hong Kong College of Obstetricians and Gynaecologists Guidelines for cervical cancer prevention and screening. Hong Kong Medical Journal, 30(6), 488–497. https://doi.org/10.12809/hkmj2411547
Ott, J. J., Stevens, G. A., & Wiersma, S. T. (2012). The risk of perinatal hepatitis B virus transmission: hepatitis B e antigen (HBeAg) prevalence estimates for all world regions. BMC Infectious Diseases, 12. https://doi.org/10.1186/1471-2334-12-131
Sekarini, N. N. A. D., Yanti, L., & Pratiwi, P. I. (2025). Knowledge and attitude factors as determinants of pregnant women’s articipation in triple elimination program in North Bali. BIO Web of Conferences, 152, 1–9. https://doi.org/10.1051/bioconf/202515201022
Shibabaw, A. A., Tegegne, M. D., Walle, A. D., Wubante, S. M., Baykemagn, N. D., Sisay, M. M., & Weldeab, A. N. (2024). Information seeking behavior on hepatitis B virus, and its associated factors among pregnant women at teaching and specialized hospitals, Northwest Ethiopia: A cross-sectional study. PLoS ONE, 19(1 January), 1–17. https://doi.org/10.1371/journal.pone.0286755
Temesgen, M. M., Legesse, M., Haile, A. F., Shiferaw, B., & Dessie, T. (2025). Risk factors associated with hepatitis B virus infection among patients attending gastroenterology outpatient department at public hospitals in Northeast Ethiopia?: a hospital-based unmatched case-control study.
Tochukwu, E. J., Onyinye, E. N., & Obinna, O. E. (2024). Assessing the awareness and acceptability of hepatitis B immunoglobulin among pregnant women in Enugu metropolis, Southeast, Nigeria: A cross-sectional study. SAGE Open Medicine, 12. https://doi.org/10.1177/20503121241257083
World Health Organization. (2024). Global Hepatitis Report 2024. https://www.who.int/publications/i/item/9789240091672
Downloads
Published
How to Cite
Issue
Section
Citation Check
License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Upon the acceptance of the article by the Editorial Board of Jurnal Kesehatan Prima and the decision to publish it, the copyright for the article will be transferred to Jurnal Kesehatan Prima, published by Poltekkes kemenkes Mataram. Poltekkes kemenkes Mataram as the publisher of Jurnal Kesehatan Prima holds the copyright to all published articles in this journal.



