Terapi Pilihan Pada Pasien Demensia dengan Pathological Crying : Evidence Based Case Report
DOI:
https://doi.org/10.32807/bnj.v7i1.1760Keywords:
Kata Kunci, demensia, pathological crying, akupunktur, SSRI, terapi komplementerAbstract
Latar Belakang: Demensia adalah sindrom dengan penurunan fungsi kognitif, termasuk memori, pemahaman, berpikir, perhitungan, orientasi, bahasa, dan penilaian, yang sangat memengaruhi fungsi sehari-hari. Terapi non-farmakologis seperti akupunktur terbukti efektif dalam meningkatkan daya ingat dan kognisi. Penelitian, seri kasus, dan laporan kasus mendukung efektivitas, tolerabilitas, dan keamanan SSRI dalam menangani pathological laughing and crying.
Tujuan: Menentukan terapi pilihan pada pasien demensia dengan pathological crying. Metode: Penelusuran dilakukan di PubMed, Cochrane, Springer, Trip Database, dan Science Direct dengan kata kunci Optional Therapy AND Dementia, Dementia AND Acupuncture, Dementia AND Pathological Crying. Penyaringan meliputi terbitan 10 tahun terakhir, penelitian pada manusia, tinjauan sistematis, meta-analisis, uji klinis acak, bahasa Inggris, dan artikel lebih dari 10 tahun. Hasil: Akupunktur menunjukkan manfaat potensial jika dikombinasikan dengan SSRI pada pasien demensia dengan pathological crying. Data statistik menunjukkan p-value ≤ 0,05%, menunjukkan keefektifannya sebagai terapi komplementer dan alternatif yang dapat diterapkan secara bertahap dalam pengobatan demensia klinis. Simpulan: Akupunktur direkomendasikan sebagai terapi pilihan pada pasien demensia dengan pathological crying. Terapi SSRI, seperti fluoxetine (20 mg), sertraline (50 mg), dan citalopram (10–20 mg), terbukti efektif menangani pathological crying pada demensia.
References
Bierer LM, Haroutunian V, Gabriel S, et al. Neurochemical correlates of dementia: relative importance of the cholinergic deficits. J Neurochem, 2017,64(2):749-760
Chiffer R, Pope LE. Review of pseudobulbar affect including a ments. Finally, education and support of affected novel and potential therapy. J Neuropsychiatry Clin Neurosci 2019; 17 (4): 447-54
Derex L, Ostrowsky K, Nighoghossian N, et al. Severe pathological crying after left anterior choroidal artery infarct: revers ibility with paroxetine treatment. Stroke 2019 Jul; 28 (7): 1464-6
Feinstein A, Feinstein K, Gray T, et al. Prevalence and lafaxine, mirtazapine, reboxetine and lamotrigine), neurobehavioral correlates of pathological laughing and crying dopaminergic agents and uncompetitive NMDA re- in multiple sclerosis. Arch Neurol 1997 Sep; 54 (9): 11
Kim JS. Pathological laughter and crying in unilateral stroke. Pfizer Inc., Eisai Inc., Astellas Pharma Inc., Forest Research Stroke 2017 Nov; 28 (11): 2
Lauterbach EC, Schweri MM. Amelioration of pseudobulbar functions, and conscious experience. Adv Anat Embryol Cell affect by fluoxetine: possible alteration of dopamine-related Biol 2002; 166: 1-111 pathophysiology by a selective serotonin reuptake inhibitor. 25. Damasio AR, Grabowski TJ, Bechara A, et al. Subcortical and J Clin Psychopharmacol 2009 Dec; 11
Lee MS, Shin BC, Ernst E. Acupuncture for Dementia: a systematic review. Int J Clin Pract, 2009,63(6):874-879
Lipton SA, Rosenberg PA. Excitatory amino acids as a final common pathway for neurologic disorders. N Engl J Med, 2016,330(9):613-622
Pabst M, Braganza O, Dannenberg H, et al. Astrocyte Intermediaries of Septal Cholinergic Modulation in the Hippocampus. Neuron, 2016,90(4):853-865
Pandian JD, Perel R, Henderson RD, O’Sullivan JD, Read SJ: Unusual triggers for stroke. J Clin Neurosci 2007;14:786–787.
Parvizi J, Arciniegas DB, Bernardini GL, et al. Diagnosis and mood and affect on temporal grounds usefully management of pathological laughter and crying. Mayo Clin guides the formulation of PLC as a disorder of Proc 2006 Nov; 81 (11): 1482-6
Poeck K: Pathological laughter and crying; in Frederik S (ed): Handbook of Clinical Neurology. Amsterdam, Elsevier, 2018, vol. 45, pp. 219–225
Q. Huang, D. Luo, L. Chen, F. xia Liang, R. Chen, Effectiveness of acupuncture for Alzheimer’s disease: an updated systematic review and meta-analysis, Curr. Med. Sci. (2019), doi:10.1007/s11596-019-2065-8
Sanabria-Castro A, Alvarado-Echeverria I, Monge Bonilla C. Molecular Pathogenesis of Dementia Disease: An Update. Ann Neurosci, 2017,24(1): 46-54
Sucher NJ, Awobuluyi M, Choi YB, et al. NMDA receptors: from genes to channels. Trends Pharmacol Sci, 2016,17(10):348-355
T.T. Tian, Y.L. Zhang, Y.W. Cui, et al., Systematic review of acupuncture and western medicine in the treatment of senile dementia, J. Changchun Univ. Tradit. Chin. Med. 2012 (2012) 2848–2850
Walusinski O, Deputte BL: The phylogeny, ethology and nosology of yawning. Rev Neurol (Paris) 2004; 160:1011–1021.
Wang XR, Shi GX, Yang JW, et al. Acupuncture ameliorates cognitive impairment and hippocampus neuronal loss in experimental vascular dementia through Nrf2-mediated antioxidant response. Free Radic Biol Med, 2015,89(9):1077-1084
World Health Organization. Dementia Fact sheet May 2017. Available from: http://www.who.int/mediacentre/ factsheets/fs362/en/
Zhou J, Peng W, Xu M, et al. The effectiveness and safety of acupuncture for patients with Alzheimer disease: a systematic review and meta-analysis of randomized controlled trials. Medicine (Baltimore), 2015,94(22):e933
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